Metronidazole for Dogs: What You Need to Know
Metronidazole is a common antibiotic vets prescribe for certain infections and gut problems in dogs. It works well against anaerobic bacteria and some parasites, so you’ll often see it used for diarrhea, bacterial overgrowth, and specific infections like Giardia. But it’s not a cure-all, and using it correctly matters.
When vets choose metronidazole
Vets pick metronidazole when they suspect or confirm anaerobic bacteria or protozoal infections. It’s useful for short-term control of diarrhea linked to infection, for treating some dental infections, and as part of combo therapy for certain intestinal conditions. Your vet will decide if it’s the right choice based on exam findings, stool tests, or other diagnostics.
Before starting treatment, tell your vet about other medicines your dog takes, any liver problems, or if the dog is pregnant or nursing. Metronidazole is processed by the liver, so underlying liver disease can change how the drug affects your pet.
Dosage, safety, and common side effects
Dosage depends on your dog’s weight, the condition being treated, and vet judgment. A commonly used range is roughly 10–15 mg per kg given twice daily, but some infections require different schedules. Never adjust the dose or stop early without discussing it with your vet.
Common side effects include mild stomach upset, nausea, decreased appetite, and sometimes diarrhea. More serious reactions are rare but possible — look for wobbliness, head tilt, tremors, or seizures. These can mean neurologic side effects, and you should contact your vet immediately if they appear.
Also watch for allergic reactions (hives, swelling, trouble breathing). If you see those signs, seek emergency care right away.
Give the medicine exactly as your vet instructs. Some dogs handle the pill better with food. Don’t crush or mix tablets unless your vet or pharmacist says it’s safe. Human formulations exist, but only use them when your vet approves — strength and additives can differ.
Finish the entire course even if your dog looks better, unless your vet tells you otherwise. Stopping early can let the infection come back or encourage resistant bacteria.
Store metronidazole at room temperature, in a dry place away from children and pets. Keep leftover pills in their original packaging and return unused meds to your vet or follow local disposal rules.
If your dog has liver disease, is on multiple medications, or shows any worrying signs while on metronidazole, call your vet. Clear communication and following instructions keep treatment safe and effective. If you’re unsure why the drug was prescribed or how long to give it, a quick call to your clinic will clear things up.